Anti-CCR5 Therapy Circumvents Immune Cell Exploitation by Tumors.
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چکیده
CCL5 produced by T cells at invasive margins of colorectal cancer metastases promotes tumor growth.
منابع مشابه
Advances in immunotherapeutic strategies for colorectal cancer commentary on: tumoral immune cell exploitation in colorectal cancer metastases can be targeted effectively by anti-CCR5 therapy in cancer patients by Halama et al
Colorectal cancer is a leading cause of cancer-related death in the United States, despite recent advances in treatment strategies. The immune system has been implicated in the pathogenesis of colorectal cancer, with numerous studies identifying either antagonistic or pro-tumorigenic effects of infiltrating immune cells. Therapeutic strategies harnessing the immune system to target cancers have...
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عنوان ژورنال:
- Cancer discovery
دوره 6 6 شماره
صفحات -
تاریخ انتشار 2016